fMRI neuronal adaptation. An example for neuronal adaptation can be found . In the study, long time (e.g. 5min) adaptation effects have been studied in the amblyopic cortex.
General linear model (GLM) is one of the regression methods which has been applied for detecting fMRI activation. In GLM, a predefined design matrix need to be specified. Usually, a HRF is included in the design matrix to quantify the brain response in each voxel.